Research
Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer
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* Corresponding author: Karen D Tsuchiya karen.tsuchiya@seattlechildrens.org
1 Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
2 Department of Urologic Surgery and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
3 Department of Urologic Sciences, University of British Columbia, The Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada
4 Clinical Research Division, Fred Hutchinson Cancer Research Center and Department of Laboratories, Seattle Children's Hospital, WA, USA
5 Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, USA
Molecular Cytogenetics 2009, 2:18 doi:10.1186/1755-8166-2-18
Published: 26 September 2009Additional files
Additional file 1:
Weighted scoring for the selection of candidate genes in 2E5-2F3. Detailed description of the weighted scoring method that was used to select candidate suppressor genes in the differentially deleted region of chromosome 2 between metastasizing and non-metastasizing allografts.
Format: DOC Size: 24KB Download file
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Additional file 2:
T-test sliding window whole genome and chromosome 2 analysis. Comparison of expression array results between metastatic and non-metastatic allografts using a T-test sliding window analysis.
Format: PPT Size: 333KB Download file
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Additional file 3:
Complete candidate gene list. Complete list of candidate genes from the 2E5-2F3 identified from the function-based bioinformatics filter and the cancer expression signature filter.
Format: DOC Size: 52KB Download file
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