Figure 1.

Results of FISH. A: DOP amplified BAC clone (BAC RP11-393B19) labelled with SpectrumOrange™- dUTP by means of the DOP4 primer in a PCR amplification reaction; B: DOP amplified BAC clone (BAC RP11-393B19) labelled with SpectrumOrange™- dUTP with the optimized protocol; C: DOP amplified BAC clone (BAC RP11-303I4) labelled with biotin d-CTP using the DOP4 primer in a PCR amplification reaction.; D: DOP amplified BAC clone (BAC RP11-303I4) labelled with biotin d-CTP with the optimized protocol.