Table 1

Summary of FISH studies using site-specific DNA probes.

DNA probe
Mapped
chromosome 7
t(7;21)
chromosome 21

D7Z1
7cen
+
+
--
6.3.J
7q31
+
+
--
2.6.G
7q34
+
+
--
170.4.E
7q35
+
--
--
PAC 3K23
7q36
+
--
--
D13Z1/D21Z1
13 cen and 21 cen
--
--
+
881D2
21q11.2
--
--
+
MCG-P-320-01
21q22.3
--
+
+
MCG-P-2C-01
21q22.3
--
+
+

DNA probes are derived from the collection of laboratory of cytogenetics of National Research Center of Mental Health RAMS [20-22] except the probe for 7q36 that was kindly provided by Dr. Lyndal Kearney (London, UK).

Vorsanova et al. Molecular Cytogenetics 2008 1:13   doi:10.1186/1755-8166-1-13